How to Apply
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Please send a copy of cover letter and CV directly to Dr. Bo Wen, [email protected]
Summary
The University Of Michigan College Of Pharmacy has a full-time opening for a research fellow in its Pharmacokinetics and Mass Spectrometry Core Facility (PKMS, www.pkcore.org). In this position, the candidates will learn strategies and techniques for LC-MS analysis, drug optimization and lead drug candidate selection, pharmacokinetics and drug metabolism, clinical sample analysis and clinical pharmacokinetics, and mass spectrometry imaging of small molecules, endogenous metabolites, lipids, proteins on tissue sections.
What You'll Do
- LC-MS bioanalysis method development, validation, and samples analysis to clinical studies;
- metabolite identification using LC-MS/MS in microsomal incubation and in vivo biological matrix;
- mass spectrometry imaging of small molecules from tissue samples;
- quantitative LC-MS analysis of compounds in biological matrix of preclinical samples;
- preclinical and clinical pharmacokinetic analysis;
- in vivo animal PK study samples analysis by working with animal team;
- targeted metabolomics studies for routine quantitation of well characterized metabolite, or untargeted metabolomics to discover biomarkers;
- independent preparation of study reports.
Required Qualifications*
- PhD degree (with 0-3 years experience) in analytical chemistry, chemistry, pharmaceutical sciences, pharmacology and related field.
- LC-MS skill, knowledge, and experience for small or large molecules are required.
- The candidate should be a team player with strong oral and written communication skills.
Desired Qualifications*
- Knowledge and experience in metabolite identification and pharmacokinetics are preferred.
- Knowledge and experience in high resolution mass spectrometry, metabolomics, lipidomics and proteomics are preferred.
- Knowledge and experience in mass spectrometry imaging with MALDI, DESI and high resolution mass spectrometry is a plus.
- Ability to work closely with others in a small team setting.
Background Screening
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.